PRODUCTs Overview

All Villani products have been developed by the founder of the company, Maria Villani, after her 18-years-long investigation of the effects of bioactive compounds and secondary metabolites of aquatic sponges. All products contain sponge-derived compounds with properties, that are beneficial for various skin and hair conditions, such as antibacterial, antiviral, debriding, healing and regenerative .  Some of the products contain unique microscopic needle-like particles, which are scientifically sized to penetrate the upper layer of epidermis. The micro-particles act as a delivery vehicles for the sponge-derived soluble compounds; activate a normal restorative wound-healing response in the skin, which triggers collagen and elastic production; and create temporary trans-dermal channels for enhanced permeation of the skin. 

Villani Sponge Matrix™  (VSM)™ Powder and VSM™ Extract are just some examples of proprietary products, formulated for out-license partners.  In powder form, these products contain sponge-derived compounds of different solubility and bioactivity.  The compounds can be extracted by various solvents to result in chemically different products. Using different solvents and protocols of extraction, Villani has also developed processes to result in sponge extracts with varying properties, which are used in skincare products to address skin-specific needs.  

Villani has entered into a licensing agreement with Dermata Therapeutics for the use of its patented sponge-derived product to develop various prescription products in the area of dermatology.  The first sponge-derived drug that Dermata plans to develop is a topical prescription product for the treatment of moderate and severe acne vulgaris.

Villani also entered into a licensing agreement with Villani Medical for marketing and selling professional skin care products.

OUR PIPELINE

DERMATA PRODUCT

Novel Drug for Acne Vulgaris

  DMT310

DMT310

DMT310 is a topical sponge product that Dermata plans to develop for moderate to severe acne vulgaris. It contains a rare variant of freshwater sponge that is harvested from a protected location, under strict environmental conditions, using a stringent processing protocol.  Based on her years of research, the founder of the company, Maria Villani, who discovered this unique sponge, has found that harvesting this sponge from a consistent location at a particular time of year based on the monitoring of certain environmental conditions, such as outside air temperature, water temperature, dew point, relative humidity, actual and forecasted precipitation, and wind speed and direction, results in this sponge variant having a uniform chemical profile  from batch to batch and year to year. The uniform chemical profile of this patent protected sponge will play an important role in successfully developing DMT310 as a prescription product for the treatment of patients with moderate to severe acne vulgaris. 

VILLANI MEDICAL PRODUCT

VSM™ for Villani Treatment™

  VSM™ for Villani Treatment™

VSM™ for Villani Treatment™

VSM™ Powder has a unique combination of therapeutic properties. It is used by medical professionals in the in-office resurfacing & rejuvenating procedure called the Villani Treatment™. Upon massaging reconstituted VSM™ Powder into the skin, uniformly sized microparticles (the sponge natural skeleton) penetrate the epidermis. The VSM Microparticles™ increase the production of elastin and collagen without causing injury.  In addition, the penetration of VSM Microparticles™: a) delivers bioactive compounds deeper into the skin, b) increases blood flow, c) accelerates skin turnover, d) reduces keratinocytes cohesion, and e) facilitates resurfacing of the top epidermal layer.  VSM Microparticles™ shed off together with sloughing loose keratinocytes within the next 5 days, opening pores and revealing new rejuvenated skin. The net effect is enhanced aesthetic appearance all without the typical downtime and adverse effects associated with other resurfacing & rejuvenating modalities.

VILLANI MEDICAL PRODUCT

Anti-Bruising Suite

  VSM  ™ Anti-Bruising Suite   - in development

VSM™ Anti-Bruising Suite - in development

Anti-Bruising Suite is a two step treatment recommended by dermatologists and plastic surgeons to speed recovery of bruising, pain and swelling, which often occur after other aesthetic procedures, such as rhinoplasty (nose reconstruction), blepharoplasty (eye lift), rhytidectomy (face-lift) and injection of dermal fillers. The first step is an in-office procedure, which is similar to the Villani Treatment™, but specifically formulated to treat bruises. Following the procedure, patients observe erythema, which is due to the increased blood circulation in the treated skin. Vasodilation is an important means by which bruises, stagnant spots, and infiltrates are exposed to increased blood flow.

The second step is the application of a hydrogel mask saturated with professional potency Arnica Montana and other healing ingredients. This step can be performed by a patient in the privacy and convenience of his or her home. The VSM Microparticles™ that remain in the skin after the in-office anti-bruising procedure facilitate deeper penetration of the Arnica Montana active ingredients, resulting in rapid resolve of bruises, stagnant spots, and infiltrates.

Post-Treatment Care

VILLANI MEDICAL PRODUCTS

  Villani Post-Treatment Care™ - in development

Villani Post-Treatment Care™ - in development

Post-Treatment Care is a regimen of take-home products that provide patients with convenient regimen for skin care following the Villani Treatment™ in-office resurfacing and exfoliating procedure. They contain the exclusive VSM Extract™ in its most active form.  These products aid in the restoration, renewal, and optimization of the skin.  Use of these products is highly recommended to achieve the best possible results and minimize downtime associated with exfoliation.  These post-treatment products are rich in sponge-derived compounds that are beneficial for the skin.  Nourishing proteins, sea-derived vitamins, anti-oxidants, minerals and nutrients in the formulations replenish the skin with the elements essential for beautiful and healthy skin. Every ingredient and formula used in the post-treatment products has been thoroughly reviewed and tested by chemists, toxicologists, clinicians, pharmacists and physicians for safety and effectiveness.

VILLANI MEDICAL PRODUCTS

Professional Skincare 

  Villani Professional Skincare™ - in development

Villani Professional Skincare™ - in development

Professional Skincare are dermatologists recommended take-home lines of products that contain the exclusive VSM Extract™ and specifically formulated for the following skin conditions:

•        Anti-Aging

•        Sun-Damage and Hyperpigmentation

•        Plastic Surgery Recovery

Villani Hands™ Treatment

VILLANI MEDICAL PRODUCTS

  Villani Hands™ Treatment- in development

Villani Hands™ Treatment- in development

Villani Hands™ Treatment is a resurfacing & rejuvenating procedure that can be combined by medical professionals with other procedures for hands resurfacing and rejuvenation.

Villani Hands™ Treatment works causes deep exfoliation of the brown spots without ablation of top layer of the skin.  When combined with other resurfacing and rejuvenating professional procedures,  Villani Hands™ Treatment enhances results when compared to other procedures alone.

VILLANI MEDICAL PRODUCTS

  V-PACK  ™ - Villani At-Home Treatment System™ - in development

V-PACK™ - Villani At-Home Treatment System™ - in development

V-PACK™ - Villani At-Home Treatment System™

Villani At-Home Treatment System™ is being developed in response to overwhelming demand from patients and physician alike for a consumer-friendly version of the Villani Treatment™, which patients and consumers can use safely at home either as a standalone treatment or for maintenance between the professional in-office Villani Treatments™. The system consists of a pack of 4 of the Villani At-Home Treatments™. In addition, an emollient cleanser, toner, post-treatment soothing gel, healing moisturizer, exfoliator, and intensive serum are being developed to complement the Villani At-Home Treatments™ for optimal results. All products will contain the proprietary sponge-derived VSM™ Extract. The Villani At-Home Treatment™ has 50% of strength of the professional Villani Treatment™. The reconstitution of the Villani At-Home Treatment™ with a diluent specifically formulated for the Villani At-Home Treatment™ results in a chemically different product from that in the professional Villani Treatment™.  The VSM Microparticles™ of the Villani At-Home Treatment™ are sized differently from that in the Villani Treatment. ™

VILLANI PRODUCTS

Scalp and Hair Care Products

  Villani   Scalp and Hair Care  ™ Products - in development

Villani Scalp and Hair Care™ Products - in development

Villani is in the final stage of development of the Scalp and Hair Careproducts, which contain a proprietary sponge-derived ingredients.  The products are being formulated for the prevention of hair loss and stimulation of hair growth. The hero product is the Scalp Treatment, developed to clear the hair follicles of the debris and increase blood circulation in the skin of the scalp with the goal of hair growth and prevention of hair loss. 

Complementary products containing sponge-derived extract along with other nutrients beneficial for the hair and scalp include shampoo and conditioner.

 

PORIFERA™ - Skincare For Men

VILLANI PRODUCTS

  Porifera  ™   Skincare   - in development

Porifera Skincare - in development

Villani is in the final stage of development of PORIFERA™ - Skincare For Men products for facial care, which contains a proprietary sponge-derived ingredients.  The products line includes a mask, exfoliator, moisturizer, and sunscreen, specifically formulated for men's skin to prevent ingrown hair after shaving, blemishes, and sun damage, as well as to moisturize and keep skin healthy.

Maria Villani Dermatolgy™

VILLANI PRODUCTS

MVDErmatology antiaging.JPG

Maria Villani Dermatolgy™ is a consumer brand that consists of three lines of products or system.

Antiaging System - in development.

 

MVP4_06ok1.jpg

Brightening System- in development.

plastic surgery system.JPG

Plastic Surgery Recovery System - in development.